I started Stelara this past spring after Humira treatment began to fail. The first infusion (load dose) went fine and I was given benadryl. First injection, I had a little injection site reddness. 56 days later and next injection I had itching on both sides of stomach and around injection site for a few weeks. Then next injection, I had extreme itching. I guess I thought the reaction should get better, not worse over time and the Stelara was helping my crohns symptoms. The final injection I had the worst reaction but not immediate. It started with itching for a week, then the next went up my neck and my face and lips swelled. The rash blistered a bit and I had what looked liked chicken pox.
I was seen by a derm, my GI, and immunologist. All agreed it was the stelara and I should be taken off. I was treated with Prednisone and topical cream. I do not have antibodies for Remicade so am going back on it (I took it almost 10 years ago).
I have been off the Stelara but the rash continues. I have finished the prednisone course. They are now wondering if the Stelara and my reaction triggered another type of autoimmune skin condition, I will be doing a biopsy next week.
Anyone else have a reaction like this to a biologic? I have never had skin issues. Thank you
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