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Lichen Sclerosus & Crohn's


Fri, February 28, 2025 10:39 PM


Looking to see if anyone else is dealing with lichen sclerosus and Crohn's.  Lichen sclerosus (LS) diagnosed by biopsy.  Topical steroids (Clobetasol, Fluorocinonide) are really not working.  I have now developed pustular psoriasis and plaque psoriasis as well. (Also have Sjogren's, Hashimoto's and Raynaud's, but not as bothersome).  
 Have been on Humira (or biosimilar) for 7 years. Treatment proposed for psoriasis is Wynzora (anhydrous calcipotriene and betamethasone dipropionate).  Yet another horrendously expensive drug.  The most bothersome of all these diseases is the LS.
I go to a gastroenterologist, dermatologist, gynocologist ,opthamologist and primary care (internal medecine) each of whom has prescribed a drug for their specialty area disease.
Any thoughts on LS in the universe of Crohn's? Despite the above, I am doing well, just really itchy.

FPO monarch14
Joined Sep 15, 2014

Wed, October 22, 2025 3:45 AM

Reply posted for monarch14.

The connection between autoimmune conditions like these can complicate treatment. If steroids aren’t working, it might be worth discussing other biologics or treatments that target immune pathways more directly.

FPO Thatche
Joined Oct 22, 2025

Wed, October 22, 2025 3:44 AM

Reply posted for freddyReturns23.

If steroids aren’t working, it might be worth discussing other biologics or treatments that target immune pathways more directly.

FPO Thatche
Joined Oct 22, 2025

Wed, September 10, 2025 11:07 PM

Reply posted for monarch14.

Have you discussed a coordinated approach with a specialist who can oversee all your treatments together? Sometimes a multidisciplinary plan can help target the most bothersome symptoms like LS more effectively.

FPO freddyReturns23
Joined Sep 10, 2025

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