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Starting Mercaptopurine today... scared


Thu, February 23, 2017 12:10 PM

I have moderate to severe UC and I'm in the 4th month of a pretty stubborn flare. I'm starting 6-MP this evening and I'm very nervous about it. I realize that everyone reacts to medication differently, so I might just have to wait and see how I feel. That being said, I'd still like to try and ease my fears by hearing about other people's experiences with this drug.

FPO dewsnow
Joined Feb 23, 2017

Tue, March 18, 2025 2:24 AM

Reply posted for dewsnow.

I totally understand your fears! I started taking a new medicine recently, and it was quite scary at first, but as time went on, I grew used to it. I also found that having a good support group and sound information helped dispel my fears. Just as companies need the best plans, being led by the right information is crucial. As a side note, I was looking for the cheapest Google My Business agency for my own small business to get noticed wow, so much they can do to help get trusted advice! Be strong, you've got it.


FPO yasserbadhaz
Joined Mar 18, 2025

Wed, February 26, 2025 2:25 AM

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FPO davidcameron01
Joined Dec 23, 2024

Tue, December 29, 2020 1:14 AM

Reply posted for dewsnow.

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FPO ZacharyDixon
Joined Dec 24, 2020

Thu, March 02, 2017 2:16 PM

 Reply posted for michellejackson.

Thanks for replying!  Right now my UC is mild to moderately active, but that's attributable to Prednisone. I've not been able to taper yet, so we'll see how the 6MP holds up in a few months. Perhaps I should adjust my expectations about achieving remission again. Maybe achieving mild-moderate UC off Prednisone should be my new goal. The thought of that makes me sad, but I can retrain my brain... This disease is so much harder than I thought it would be when I was first diagnosed.

FPO dewsnow
Joined Feb 23, 2017

Thu, March 02, 2017 2:03 PM

 Reply posted for nixs0717.

Thanks for your reply. I've felt super tired since I started with the meds on Friday. I've also not had much of an appetite, so I've been sort of pep talking myself to eat. Today has been my best day so far, having eaten well and my energy level has been pretty good. Remicade worked really well for me for about 2 years, but it stopped being effective in November 2016. It's been rough since, but maybe things will begin looking up with 6MP. Good luck to you!

FPO dewsnow
Joined Feb 23, 2017

Thu, March 02, 2017 1:41 PM

 Reply posted for dewsnow.

I started 6-MP this past Saturday.  That day I felt just kind of BLAH....  Since then I have been fine.  I start Remicade next week.

FPO nixs0717
Joined Mar 2, 2017

Tue, February 28, 2017 11:45 AM

 Reply posted for dewsnow.

I am on Mercaptopurine, and it's really helped get my colitis from severely active to moderately active. My doctor is careful to check my white blood count when on it. I've had to decrease my dosage to make sure my counts get too low. But this drug has definitely helped me. Good luck to you!

FPO michellejackson
Joined Feb 28, 2017

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