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Flare-up unresponsive to Prednisolone?


Fri, October 18, 2019 4:16 AM

Dear All, 

I was diagnosed with IBD about 10 years ago, and have been in total remission for years. I have now a nasty flare up with inflammation in the rectal area. I have been on large doses of Medrol, we started with 125mg shots on the first week then changed to oral 48 mg for the second, which I am now tapering gradually.  I am in the 3rd week now, and I cant feel any change, no response to the inflammation, not even side effects (apart from sleeping issues).

I have used Medrol in the past, and even a smallee dose had a clinical respone within a week or two.  Does anyone have similar experience, when Prednisolon just stopped working?

FPO SteveCH
Joined Oct 18, 2019

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